To the near frontier

We take the first steps with technical founders. We invest $400K to $1M at pre-Seed and Seed.

We are enthralled by hero(in)es whose spark can unlock the potential in science, industry, and humanity.

We partner with story-makers whose narratives might weave into the larger fabric of history.

Our capital and energies are dedicated to these endeavors and what will be written of them.

Cantos is a first-round venture capital firm with $50 million under management that invests where the innovation curve casts previously intractable problems in new light –– where new technology might positively impact billions. At a time when venture capital has become synonymous with growth equity, we exist to take the first steps with founders on bold journeys that would have been impossible just years prior. That is, to return venture capital to its roots.

clean tech

Bio + AI

Current interests


Portfolio Companies

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AI construction planning

ALICE is an intelligent software to help plan and schedule construction projects faster and cheaper by automating and optimizing crucial processes.


Better batteries

Advano has developed a silicon-based scalable solution for significantly increasing Li-Ion battery capacity.


AI for drug production

Aizon is a platform for acquiring, visualizing, and recording regulated data from manufacturing sites. It analyzes that data in real time to detect inefficiencies and identifies opportunities for improvement.


Decision based agriculture

From crop monitoring and point precision weather to cloud technology, Arable provides a complete approach to crop management in one reliable device and software solution.


satellite broadband

Astranis is pioneering GEO-based microsatellites to connect the next four billion internet users


scalable quantum computing

Atom Computing is building quantum computers using individually controlled atoms-- nature's perfect quantum bits.


Orbital transit vehicles

Atomos is designing a constellation of orbital transit vehicles to reposition satellites on orbit that will ultimately use nuclear propulsion


Biological computing

Catalog Technologies is developing DNA-based digital storage and computation.


Gene therapy delivery

Chameleon Biosciences is developing a better gene therapy delivery platform that allows for repeat dosing in patients.


Gene optimization

Using the power of circular RNA to control any gene, in any species, in any cell type.


Clinical trial enrollment

Clara streamlines the process of connecting patients with the right clinical trial so that they can access cutting edge care.

Clover Tx

Genomic medicine

Developing innovative medicines for diseases of aging.


Smarter hearables

Concha labs has built a better solution to hearing loss. With self-fitting technology and connected devices that give you control over your sound profile, Concha allows you to hear clearly again.

Curie Co

Greener preservatives

Curie Co uses proprietary enzyme engineering and synthetic biology techniques to replace chemical-based antimicrobials banned by the FDA in personal care products.

Debut Bio

Cell-free chemistry

Debut creates high-value molecules by combining proprietary enzyme immobilization with continuous biomanufacturing processes.


Construction robotics

Dusty Robotics is on a mission to improve construction productivity by automating critical-path tasks on construction jobsites.

Earth AI

AI for mining

Earth AI is discovering deposits of metals using vertically integrated technologies for fast and efficient discovery


5G & beyond

Eridan's software-defined radio offers fast, reliable wireless connectivity with a fraction of the energy.


Sustainable investing

Ethic is a data-driven technology platform that creates simple, custom-built, returns-driven passive portfolios for sustainability-focused investors.


Nutritional oncology

Using metabolism to rethink the science of cancer


Protein sequencing

Unlocking proteomics by lowering protein sequencing costs.


[In stealth]

Stay connected, stay present


The chemicals marketplace

Knowde is the world's largest chemicals database, where buyers and sellers in this $5T industry connect.

Mission Barns

Cultured Meat

Mission Barns is making the juicy, savory meats we all love in a sustainable, more efficient way.


AI for drug discovery

Phenomic leverages computer vision, AI, and deep learning to unlock novel drug targets

Pow Bio

Bio-manufacturing provides intelligent fermentation services for industrial and synthetic biology, helping turn great ideas into profitable products.


High fidelity bio-printing

Prellis Biologics is engineering human tissue using a laser-based 3D printing technology capable of vasculature-level definition.


A new way to invest

Public makes the stock market social.

Sixfold Bio

RNA therapeutics

Delivering RNA therapies to treat any disease, starting with cancer


Democratizing flight

SkyRyse is building a future free from congestion and infrastructure sprawl, starting with standardizing flight controls with their FlightOS platform


Plant-based chemicals

Solugen is replacing petroleum based products with plant-derived substitutes, taking advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products.

Space Tango

Zero-G R&D

Space Tango's ISS-based system streamlines and simplifies the unique environment that microgravity offers to discover and commercialize solutions for applications on earth.

Standard Cyborg

Computer vision

Standard Cyborg is the complete solution for integrating 2D and 3D data.


Intelligent robotics

Symbio is dedicated to strengthening industrial systems through the development of robotics and artificial intelligence.


Plant-based bio manufacturing

Expressing high-value biological compounds in plants grown in vertical farms.


Products from CO2

Twelve (formerly Opus 12) has developed a device that recycles CO₂ into cost-competitive chemicals and fuels with only water and electricity as inputs.


Autonomous farm management

Vence is bringing artificial intelligence to the livestock industry to optimize farming activities and increase animal well-being.


Hypersonic flight

Venus is a team of veteran aerospace engineers and operators working toward military and civilian flight at Mach 15.


Carbon negative materials

Visolis' technology enables bio-based production of carbon-negative, high-performance polymers at lower costs than petrochemical processes.

X Genomes

AI-driven sequencing

Using proprietary chemistry, AI, and computer vision, X Genomes is making sequencing more efficient and affordable