We invest in near frontier tech that will change the world.

Some call it deep tech. We think of it as near frontier. We believe science-forward companies are our best shot at improving billions of lives and saving the planet. We back them at pre-seed & seed.
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Better batteries
Advano has developed a silicon-based scalable solution for significantly increasing Li-Ion battery capacity.
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Decision based agriculture
From crop monitoring and point precision weather to cloud technology, Arable provides a complete approach to crop management in one reliable device and software solution.
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Carbon-negative energy
Arbor converts organic waste into clean energy and water while permanently removing CO2 from the atmosphere
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satellite broadband
Astranis is pioneering GEO-based microsatellites to connect the next four billion internet users.
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Atom Computing
scalable quantum computing
Atom Computing is building quantum computers using individually controlled atoms-- nature's perfect quantum bits.
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Atomos Space
Orbital transfer vehicles
Atomos is designing a constellation of orbital transit vehicles to reposition satellites on orbit that will ultimately use nuclear propulsion.
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Bedrock Energy
Decarbonizing buildings
Bedrock unlocks geothermal heating and cooling for any real estate in any location
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Biological computing
Catalog Technologies is developing DNA-based digital storage and computation.
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Chameleon Bio
Gene therapy delivery
Chameleon Biosciences is developing a better gene therapy delivery platform that allows for repeat dosing in patients.
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Character Bio
Genomic medicine
Character is developing innovative medicines for diseases of aging using genomics and computer vision.
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Curie Co
Greener preservatives
Curie Co uses proprietary enzyme engineering and synthetic biology techniques to replace chemical-based antimicrobials banned by the FDA in personal care products.
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Debut Bio
Biomanufacturing active ingredients
Debut creates high-value products like dyes, fragrances, and flavorings by combining proprietary enzyme immobilization with continuous, cell-free biomanufacturing processes.
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Construction robotics
Dusty Robotics is on a mission to improve construction productivity by automating critical-path tasks on construction jobsites.
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Earth AI
AI for mining
Earth AI is discovering deposits of metals using vertically integrated technologies for fast and efficient discovery.
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5G & beyond
Eridan's software-defined radio offers fast, reliable wireless connectivity with a fraction of the energy.
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Precision Nutrition
Faeth harnesses metabolism and personalized medicine to rethink the science of cancer.
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Electrifying ocean freight
Fleetzero is electrifying one of the world's dirtiest industries, cargo shipping, with swappable batteries.
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Furno Materials
Decarbonizing cement
Furno is designing compact, energy-efficient cement reactors to halve the energy required and capture CO2 produced in one of the most essential but most polluting industries.
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Glyphic Bio
Protein sequencing
Unlocking proteomics by lowering protein sequencing costs.
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Good AI
Humane will soon launch AI-native devices that will allow us to stay connected while remaining present.
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Electric autonomous rail
Intramotev is developing electric, autonomous railcars to solve intermodal freight bottlenecks and reduce emissions in logistics, taking trucks off the road and freeing up ports.
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Limelight Steel
Decarbonizing steel
Limelight harnesses light to power zero-emissions steel manufacturing the most CO2-intensive heavy industry
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Mako Aerospace
Electric jet engines
Mako is designing the world's most efficient electric engines for commercial aircraft to enable emission-free regional flight.
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Mission Barns
Cultured Meat
Mission Barns is making the juicy, savory meats we all love... without the animal.
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mapping the neuroimmune system
Modulo is building the map and key to our neuroimmune systems for use in treating neurodegenerative disease
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Nabla Bio
AI for antibody optimization
Nabla Bio is the world's leader in applying natural language processing (NLP) to developing therapeutic antibodies
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Breaking down cancer's wall
Phenomic leverages single cell transcriptomic data to develop drug candidates targeting the tumor stroma (aka Cancer's wall).
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Pow Bio
Pow.bio provides intelligent fermentation services for industrial and synthetic biology, helping turn great ideas into profitable products.
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High fidelity bio-printing
Prellis Biologics is engineering human tissue using a laser-based 3D printing technology capable of vasculature-level definition.
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Portable fission reactors
Radiant is building portable 1MW nuclear reactors, enough to power 1,000 homes or a military base for years.
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Resistance Bio
Understanding cancer biology
Resistance harnesses evolution to identify novel targets to fight drug-resistant cancers
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Salient Motion
Electric motor controllers
Salient Motion is designing and manufacturing ultra-reliable and high performance motor controllers
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Sixfold Bio
RNA therapeutics
Sixfold Bio develops delivery mechanisms that target RNA therapies to treat any disease in any tissue.
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Advancing aviation
Skyryse is building a future free from congestion and infrastructure sprawl, starting with standardizing flight controls and improving safety in general aviation with their FlightOS platform.
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Plant-based chemicals
Solugen is replacing petroleum based products with plant-derived substitutes, taking advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products.
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Space Tango
Space-based manufacturing
Space Tango's ISS-based system streamlines and simplifies the unique environment that microgravity offers to discover and commercialize solutions for applications on earth.
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Spaero Bio
Wet lab automation
Spaero helps scientists scale their experiments with ease using the robots already in their lab
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Plant-based bio manufacturing
Tiamat expresses high-value biological compounds in plants grown in vertical farms.
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Transforming carbon
Twelve (formerly Opus 12) has developed a device that recycles CO₂ into cost-competitive chemicals and fuels with only water and electricity as inputs.
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Venus Aerospace
Hypersonic flight
Venus is a team of veteran aerospace engineers and operators working towards hypersonic flight.
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Carbon negative materials
Visolis' technology enables bio-based production of carbon-negative, high-performance polymers at lower costs than petrochemical processes.
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We write on deep tech and talk to founders building hardware and bio startups to bring you unfiltered stories on how such companies come to life and most importantly, give us hope for the future.
Discovering Early-Stage Talent
Our talent partner Natalie Estrella sits down with KdT's head of talent Yusuf Uddin to discuss building early-stage teams in deep tech
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Mapping the Neuroimmune System
Why we invested in Modulo
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Building the BioForge w/ Sean Hunt of Solugen
Sean Hunt, co-founder and co-CEO of Solugen, shares his thoughts on the evolution of clean tech, how to build a revenue-generating deep tech business, the future of synthetic biology, and more.
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Electrification of Things—By Sea
Why we invested in electric cargo-shipping company Fleetzero
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The Fourth Pillar of Cancer w/ Anand Parikh of Faeth
Faeth CEO Anand Parikh talks to us about building a therapeutics + digital health + meal delivery company all at once and the necessity for precision nutrition in medicine.
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who we are
Ian Rountree
General Partner
Achal Upadhyaya
Venture Partner
Natalie Volpe
Venture Partner
Amee Kapadia, MS
Principal (Bio Lead)
Natalie Estrella
Talent Partner
Ha Nguyen
Tessa Lau, PhD
Dusty Robotics CEO
Sassie Duggleby, MS
Venus Aerospace CEO
Joshua Yang, M.Eng
Glyphic Bio CEO
Etosha Cave, PhD
Twelve CSO
Nicholas Flanders, MS
Twelve CEO
John Gedmark, MS
Astranis CEO
Sean Hunt, PhD
Solugen CTO
Gaurab Chakrabarti, PhD
Solugen CEO
Mark Groden, PhD
Skyryse CEO
Joshua Britton, PhD
Debut Bio CEO
Sam Cooper, PhD
Phenomic CEO
Shak Lakhani
Avro CEO