We invest in near frontier tech that will change the world.

built for technical founders tackling the world's biggest problems
Some call it deep tech. We think of it as near frontier. We believe science-forward companies are our best shot at improving billions of lives and stewarding our planet. We back them from day one.
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AI for drug production
Aizon is a platform for acquiring, visualizing, and recording regulated data from manufacturing sites. It analyzes that data in real time to detect inefficiencies and identifies opportunities for improvement.
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Apex Space
Spacecraft manufacturing
Apex manufactures standardized satellite buses configurable to operators' needs so customers can focus on what's important: their payloads
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Carbon-negative energy
Arbor converts organic waste into clean energy while permanently removing CO2 from the atmosphere
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satellite broadband
Astranis is pioneering GEO-based microsatellites to connect the next four billion internet users.
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Atom Computing
scalable quantum computing
Atom Computing is building quantum computers using individually controlled atoms-- nature's perfect quantum bits.
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Atomos Space
In-space logistics
Atomos is developing orbital transfer vehicles capable of autonomous rendezvous to reposition satellites on orbit and beyond.
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Bedrock Energy
Decarbonizing buildings
Bedrock unlocks geothermal heating and cooling for any real estate in any location
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Cache Energy
Long-duration energy storage
Cache's chemical batteries unlock insanely cheap, portable long-duration energy storage
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Biological computing
Catalog Technologies is developing DNA-based digital storage and computation.
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Character Bio
Genomic medicine
Character is developing innovative medicines for diseases of aging using genomics and computer vision.
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Curie Co
Greener preservatives
Curie Co uses proprietary enzyme engineering and synthetic biology techniques to replace chemical-based antimicrobials banned by the FDA in personal care products.
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Debut Bio
Biomanufacturing active ingredients
Debut creates high-value products like dyes, fragrances, and flavorings by combining proprietary enzyme immobilization with continuous, cell-free biomanufacturing processes.
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Dusty Robotics
Automating layout
Dusty Robotics is on a mission to improve construction productivity by automating critical-path tasks on construction jobsites.
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Earth AI
AI for mining
Earth AI is discovering deposits of metals using vertically integrated technologies for fast and efficient discovery.
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Precision Nutrition
Faeth harnesses metabolism and personalized medicine to rethink the science of cancer.
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Electrifying ocean freight
Fleetzero is electrifying one of the world's dirtiest industries, cargo shipping, with swappable batteries.
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Furno Materials
Decarbonizing cement
Furno is designing compact, energy-efficient cement reactors to halve the energy required and capture CO2 produced in one of the most essential but most polluting industries.
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Glyphic Bio
Protein sequencing
Unlocking proteomics by lowering protein sequencing costs.
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Bring AI with you
Humane's Ai Pin will allow us to stay connected while remaining present.
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Electric autonomous rail
Intramotev is developing electric, autonomous railcars to solve intermodal freight bottlenecks and reduce emissions in logistics, taking trucks off the road and freeing up ports.
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Limelight Steel
Green steel
Limelight harnesses light to power zero-emissions steel manufacturing the most CO2-intensive heavy industry
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Mission Barns
Cultured Meat
Mission Barns is making the juicy, savory meats we all love... without the animal.
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mapping the neuroimmune system
Modulo is building the map and key to our neuroimmune systems for use in treating neurodegenerative disease
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Nabla Bio
AI for antibody optimization
Nabla Bio is the world's leader in applying natural language processing (NLP) to developing therapeutic antibodies
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Breaking down cancer's wall
Phenomic leverages single cell transcriptomic data to develop drug candidates targeting the tumor stroma (aka Cancer's wall).
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Pow Bio
Pow.bio provides intelligent fermentation services for industrial and synthetic biology, helping turn great ideas into profitable products.
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High fidelity bio-printing
Prellis Biologics is engineering human tissue using a laser-based 3D printing technology capable of vasculature-level definition.
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Portable fission reactors
Radiant is building portable 1MW nuclear reactors, enough to power 1,000 homes or a military base for years.
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Resistance Bio
Understanding cancer biology
Resistance harnesses evolution to identify novel targets to fight drug-resistant cancers
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Salient Motion
Electric motor controllers
Salient Motion is designing and manufacturing ultra-reliable and high performance motor controllers
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Reinventing Fish processing
Shinkei automates artisanal techniques to scale more sustainable practices, feeding more people with less waste.
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Sixfold Bio
RNA therapeutics
Sixfold Bio develops delivery mechanisms that target RNA therapies to treat any disease in any tissue.
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Fly simple. Fly safe.
A new era in flight. Making general aviation safer and easier.
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Changing how the world sees
SoloPulse's radar processing technology dramatically improves sensing capabilities
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Plant-based chemicals
Solugen is replacing petroleum based products with plant-derived substitutes, taking advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products.
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Spaero Bio
Wet lab automation
Spaero helps scientists scale their experiments with ease using the robots already in their lab
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Plant-based bio manufacturing
Tiamat expresses high-value biological compounds in plants grown in vertical farms.
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Transforming carbon
Twelve (formerly Opus 12) has developed a device that recycles CO₂ into cost-competitive chemicals and fuels with only water and electricity as inputs.
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Venus Aerospace
Hypersonic flight
Venus is a team of veteran aerospace engineers and operators working towards hypersonic flight.
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We write on deep tech and talk to founders building hardware and bio startups to bring you unfiltered stories on how such companies come to life and most importantly, give us hope for the future.
Electric Autonomous Rail w/ Tim Luchini of Intramotev
Intramotev Co-Founder & CEO Tim Luchini talks autonomous, electric rail with Cantos' Ian Rountree
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Mapping the Neuroimmune System
Why we invested in Modulo
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Building the BioForge w/ Sean Hunt of Solugen
Sean Hunt, co-founder and co-CEO of Solugen, shares his thoughts on the evolution of clean tech, how to build a revenue-generating deep tech business, the future of synthetic biology, and more.
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Electrification of Things—By Sea
Why we invested in electric cargo-shipping company Fleetzero
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The Fourth Pillar of Cancer w/ Anand Parikh of Faeth
Faeth CEO Anand Parikh talks to us about building a therapeutics + digital health + meal delivery company all at once and the necessity for precision nutrition in medicine.
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who we are
Ian Rountree
General Partner
Amee Kapadia
Natalie Estrella
Talent Partner
Achal Upadhyaya
Special Advisor
Ha Nguyen